Dr. Jeckyll
12-01-2000, 01:46 AM
Ok, I think I have finally figured something out. GHB is ENTIRELY A RECREATIONAL DRUG.
I believe Dopamine inhibits prolactin release by binding at th D2 receptor, one of a few that is recepted by dopamine.
Ghb blocks the reception of this neurotransmitter, therefore, prolactin flows and creates a temporary state of "hyperprolactinemia."
In males, hyperprolactinemia can cause infertility, breast enlargement, possible lactation, loss of sex drive, and increased bodyfat composition.
When we take this substance all day, we put ourselves in a constant state of hyperprolactinemia.
Abnormal prolactin has been linked to breast cancer.
Growth hormone
Studies suggested that the hGH release caused by ghb were 1600% in lab rats. Ok, great. Now, would you take gh if it had estrogen or estradiol in it? I do not see how gh and prolactin can be very related. GH will not cancel out prolactin. It seems to defeat the purpose.
What can exogenous gHB do to downregulate our pituitary? We are, after all causing it to produce way to much prolactin. Prolactin has an effect on the thyroid and is why it causes an increase in fat. Does this substance cause a chain of events within the body that we never really sat back and analyzed?
Can this prolactin be blocked?
Certain people have stated that they lost weight on Gbl, Heat being one. Maybe certain people are resistant to the prolactin release. I would wonder if these people took vitamin B6 or Nickel (which possibly lowers prolactin levels in Animal studies.). I just do not think it is possible to actually alter the amount of prolactin released. It all has to do with the dopamine blockage. The only way to insure that less prolactin is released is to take smaller doses of ghb.
Withdrawal
Ghb causes withdrawals in the frequent user, case closed. When dopamine reception is blocked all day, it does not stop its actual formation. When the receptors become available again, we get the Dopamine rebound. High levels of Dopamine can cause
high blood pressure (dopamine can effect norepinephrine)
Paranoia
Obsession
Tachycardia (fast heart rate)
Tremors
And logically, I would say it would lower the efficacy of our natural serotonin.
Insomnia (dopamine is related to the mechanism that causes us to awaken.)
Look for more physical symptoms than mental addiction.
In conclusion, I think ghb is worthless as far as an alternative to hGH. I do not feel as though it is possible to make up for the release of prolactin, nor block its formation.
I took this from VaRiX where I originally posted it. Next I am going to write one up about 1,4 and gbl, and why they are different in regards to their effects. (both are converted to ghb through different liver enzymes, ethanol dehydrogenase and lactonase I believe.)
I believe Dopamine inhibits prolactin release by binding at th D2 receptor, one of a few that is recepted by dopamine.
Ghb blocks the reception of this neurotransmitter, therefore, prolactin flows and creates a temporary state of "hyperprolactinemia."
In males, hyperprolactinemia can cause infertility, breast enlargement, possible lactation, loss of sex drive, and increased bodyfat composition.
When we take this substance all day, we put ourselves in a constant state of hyperprolactinemia.
Abnormal prolactin has been linked to breast cancer.
Growth hormone
Studies suggested that the hGH release caused by ghb were 1600% in lab rats. Ok, great. Now, would you take gh if it had estrogen or estradiol in it? I do not see how gh and prolactin can be very related. GH will not cancel out prolactin. It seems to defeat the purpose.
What can exogenous gHB do to downregulate our pituitary? We are, after all causing it to produce way to much prolactin. Prolactin has an effect on the thyroid and is why it causes an increase in fat. Does this substance cause a chain of events within the body that we never really sat back and analyzed?
Can this prolactin be blocked?
Certain people have stated that they lost weight on Gbl, Heat being one. Maybe certain people are resistant to the prolactin release. I would wonder if these people took vitamin B6 or Nickel (which possibly lowers prolactin levels in Animal studies.). I just do not think it is possible to actually alter the amount of prolactin released. It all has to do with the dopamine blockage. The only way to insure that less prolactin is released is to take smaller doses of ghb.
Withdrawal
Ghb causes withdrawals in the frequent user, case closed. When dopamine reception is blocked all day, it does not stop its actual formation. When the receptors become available again, we get the Dopamine rebound. High levels of Dopamine can cause
high blood pressure (dopamine can effect norepinephrine)
Paranoia
Obsession
Tachycardia (fast heart rate)
Tremors
And logically, I would say it would lower the efficacy of our natural serotonin.
Insomnia (dopamine is related to the mechanism that causes us to awaken.)
Look for more physical symptoms than mental addiction.
In conclusion, I think ghb is worthless as far as an alternative to hGH. I do not feel as though it is possible to make up for the release of prolactin, nor block its formation.
I took this from VaRiX where I originally posted it. Next I am going to write one up about 1,4 and gbl, and why they are different in regards to their effects. (both are converted to ghb through different liver enzymes, ethanol dehydrogenase and lactonase I believe.)